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The principal efficacy endpoint.

Albireo reports excellent results from A3309 Stage IIb research in chronic idiopathic constipation Albireo today announced positive top-line results from a Phase IIb research in chronic idiopathic constipation assessing efficacy and protection of three different dosage amounts of the investigational drug A3309 during an eight week trial. Analyses of the info show clinically meaningful and statistically significant improvement for patients treated with A3309 in comparison to placebo-treated individuals. A3309 is a first-in-course IBAT inhibitor with reduced systemic exposure which is created for the treatment of CIC and constipation-predominant irritable bowel syndrome uses reviews .

While professionals agreed that criminalizing alcohol and tobacco will be challenging, they stated that governments should review the penalties imposed for drug abuse and try to make them even more reflective of the actual risks and damages involved. Nutt needed more education so that people were alert to the risks of various drugs. ‘All medications are dangerous,’ he said. ‘Even the ones people know and like and use every day.’.. Alcohol, Tobacco Worse Than Illegal Drugs? Fresh ‘landmark’ research finds that alcohol and tobacco are more threatening than some illegal medicines like marijuana or Ecstasy and should be categorized as such in legal systems, according to a fresh British study.