Following the tube was replaced, her symptoms improved immediately. Five cases of severe pancreatitis related to gastrostomy tube migration have been reported. Dr. Imamura experienced a very uncommon complication of gastrostomy tube, and this case demonstrated a malpositioned gastrostomy tube can be an iatrogenic reason behind acute pancreatitis and cholangitis.. Acute cholangitis and pancreatitis Percutaneous endoscopic gastrostomy is generally regarded as safe with a low rate of serious complications. Nevertheless, dislocation of a gastrostomy tube can lead to serious complications.The development of our study cohort previously has been described. Using a validated algorithm,23 we estimated the time of the last menstrual period based on the delivery time and diagnostic codes indicative of preterm delivery. Finally, we required all the women to qualify for Medicaid, without supplementary personal insurance or restricted benefits, from three months prior to the last menstrual period through four weeks after delivery. We excluded pregnancies in which the baby had received a medical diagnosis of a chromosomal abnormality and pregnancies where the mother had been treated with known teratogens during the initial trimester .